Zbigniew Ochocki, Andrzej Stańczak

Mechanizmy regulujące perystaltykę układu pokarmowego

Mechanisms regulating the digestive tract peristalsis. Proper digestion requires that the movement of food (peristalsis) be coordinated by the nerves and muscles that are part of the digestive tract. Digestion and peristalsis are regulated both by autonomic nervous system and hormonally. The two arms of the autonomic nervous system both influence the digestive process; parasympathetic nerves stimulate secretions and peristalsis while the sympathetic influence is more inhibitory. The major hormones that control the functions of the digestive system are produced and released by cells in the mucosa of the stomach and small intestine. The gastrointestinal tract is the largest endocrine organ in the body and the endocrine cells within it are referred to collectively as the enteric endocrine system. Three of the best-studied enteric hormones are: secretin, gastrin and cholecystokinin, are released into the blood by the digestive tract and stimulate digestive juices and cause organ movement. The important role of peristalsis function perform less known hormones as: motylin, neuorotensin (NT), amylin or vasoactive intestinal peptide (VIP).