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Overview of regulatory initiatives in the European Union to stimulate research and accelerate access to orphan drugs and other high medical need products
Aleksandra Baran-Kooiker, Coen Kooiker, Marcin Czech
WIĘCEJ
Determination of fluconazole and its oxidation products with kinetic evaluation under potassium per-manganate treatment in acidic solutions by ultra performance liquid chromatography-tandem mass spectrometry
Urszula Hubicka, Jan Krzek, Paweł Żmudzki, Barbara Żuromska-Witek, Dariusz Motyl, Agata Kryczyk
WIĘCEJ
Purity determination of the starting materials used in the synthesis of pharmaceutical substances
Aleksandra Groman, Elżbieta Stolarczyk, Mariola Mucha
WIĘCEJ
Development and validation of RP-HPLC method for simultaneous quantification of sulfacetamide sodium and prednisolone sodium phosphate
Nabiha Abdullah, Fizza Karamat, Shaista Qamar, Mateen Abbass, Abdul Muqeet Khan, Naseem Ullah
WIĘCEJ
Development and validation of stability-indicating hplc method for diflucortolone valerate and isoconazole nitrate combination
Suriye Özlem Gündogdu, Funda Şimşek, Asuman Doganay, Yilmaz Çapan
WIĘCEJ
Formulation and in vivo pharmacokinetic studies of iloperidone depot injection
Bioavailability of mesalazine from two coated formulation tablets
Franciszek K. Główka, Tadeusz W. Hermann, Jacek Hermann, Maciej Zabel
WIĘCEJ
Effects of bee venom on activity and expression of 15-lipoxygenase-1 in human HT29 colon cancer
Mohammad Soukhtanloo, Maryam Zare, Jina Khayatzadeh, Hamidreza Sadegh Nia, Majid Mojarad, Fatemeh Baghbani, Javad Sargolzaei, Hamid Sadeghian, Mohsen Sisakhti
WIĘCEJ
From harvesting to distillation - effect of analytical procedures on the yield and chemical composition of Rho-dodendron tomentosum (Ledum palustre) essential oil
Anna Jesionek, Bożena Zabiegała, Adam Buciński, Maria Łuczkiewicz
WIĘCEJ
Chemical profile and antibacterial activity of essential oils from leaves and fruits of Gaultheria procumbens L. cultivated in Poland
Anna Magiera, Monika Sienkiewicz, Monika A. Olszewska, Agnieszka Kicel, Piotr Michel
WIĘCEJ
Use of glutaric acid to improve the solubility and dissolution profile of glipizide through pharmaceutical cocrystallization
Fakhra Batool, Mahmood Ahmad, Muhammad Usman Minhas, Fahad Mehmood Khan, Hafiz Arfat Idrees, Qandeel Khalid
WIĘCEJ
Seleno-L-methionine modulate the toxic effect of new doxorubicin metal complexes in prokaryotic model - Escherichia coli RMF recA::lux
Marzena Matejczyk, Grzegorz Świderski, Włodzimierz Lewandowski
WIĘCEJ
Sildenafil upregulates tumor necrosis factor a production in peripheral blood mononuclear cells of healthy men - preliminary report
Beata Kaleta, Agnieszka Boguska, Jan Borysowski, Andrzej Górski
WIĘCEJ
Population pharmacokinetics of 25-hydroxy vitamin D in non- elderly postmenopausal women
Jelena Djokovic, Aleksandra Tomic Lucic, Olivera Z. Milovanovic, Danijela Bazic, Mirjana Veselinovic, Ale-ksandar Djukic, Sandra Matovic, Radica Zivkovic Zaric, Radmila Velickovic Radovanovic, Slobodan M. Jankovic, Jasmina R. Milovanovic
WIĘCEJ
Cocaine consumption in the city of Murcia (southeast of Spain) estimated by wastewater analysis: applying an accurate and valid tool to obtain objective data for drug abuse
Lucía Fernández-López, Javier Navarro-Zaragoza, Francisco Caravaca, María Falcón, Aurelio Luna
WIĘCEJ
The effects of sulfur-containing compounds on redox status in homocysteine-treated rats
Tanja S. Sobot, Vladimir I. Zivkovic, Ivan M. Srejovic, Jovana N. Jeremic, Tamara R. Nikolic Turnic, Nenad D. Ponorac, Anica M. Petkovic, Vladimir Lj. Jakovljevic, Dragan M. Djuric
WIĘCEJ
Comparison of cancer patients' quality of life in Hungary and Germany - a cross-national questionnaire analysis
Nuclear targeting study of HPMA copolymer-5-fluorouracil conjugate based on the subcellular distribution in PC-3 cells
Lan You, Shi-Ying Dai, Yuan Huang, Li Ming Ye, Chun-Mei Fu
WIĘCEJ
EPR study of free radicals formed in fusidic acid and neomycin under UV irradiation
Ewa Pierzchała, Paweł Ramos, Barbara Pilawa
WIĘCEJ
Temperature dependent solubility studies of brigatinib in some pure solvents useful in dosage form develop-men
Muqtader Mohammad, Md. Khalid Anwer, Farhat Fatima, Saad M. Alshahran, Abdullah S. Alshetaili, Ahmed Alalaiwe, Bader B. Alsulays, Faiyaz Shakeel
WIĘCEJ
Can angiotensin-converting enzyme inhibitors interfere with the free radicals? Measurement of antioxidant capacity using DPPH radical reduction examined by UV-Vis method
Anna Juszczak, Paweł Ramos, Wojciech Szczołko, Barbara Pilawa, Beata J. Stanisz
WIĘCEJ
Determination of paracetamol in commercial suppositories using differential scanning calorimetry
Edyta Leyk, Sebastian Komar, Marek Wesołowski
WIĘCEJ
Synthesis, immunosuppressive properties, mechanism of action and X-ray analysis of a new class of isoxazole derivatives
Urszula Bąchor, Stanisław Ryng, Marcin Mączyński, Jolanta Artym, Maja Kocięba, Ewa Zaczyńska, Iwona Kochanowska, Ewa Tykarska, Michał Zimecki
WIĘCEJ
Synthesis and anticonvulsant properties of some n-aryl and n-arylaminomethyl derivatives of 3-p-isopropoxyphenylpyrrolidine-2,5-dione
Sergey L. Kocharov, Henry Panosyan, Jarosław Chmielewski, Barbara Gworek, Jarogniew J. Łuszczki
WIĘCEJ
Fatty acids analysis and antioxidant activity of a lipid extract obtained from Mercurialis annua L. grown wildly in Jordan
Validation of hepatoprotective use of Polygonum perfoliatum extract against paracetamol induced toxicity in wistar rats
Mohammad Saleem, Muhammad Fahd Mushtaq, Muhammad Furqan Akhtar, Ammara Saleem, Sara Zahid, Ali Sharif, Bushra Akhtar, Eshwa Dar, Munair Badshah, Majeed Ullah
WIĘCEJ
In vitro antiviral and antioxidant activities of silymarin and Panax ginseng on vero cells infected with Bovine ephemeral fever virus and Bluetongue virus
Development of tablets containing solid dispersion of ibuprofen manufactured by hot melt impregnation process
Kamil Garbera, Katarzyna Woś-Latosi, Wiesław Sawicki
WIĘCEJ
A study of the combination of microcrystalline cellulose and mannitol in a co-processed dry binder and in a physical mixture for the use in orally disintegrating tabletsd
Jitka Mužikova, Andres Nowotna, Martinb Bartoš
WIĘCEJ
Health behaviour of elderly patients with heart failure in Poland associated with pharmacotherapy and non-pharmacological treatment
Magdalena Makarewicz-Wujec, Ewelina Janas, Małgorzata Kozłowska-Wojciechowska
WIĘCEJ
Influence of community pharmacy specialization on professional pharmaceutical counselling scheme in phar-macies in Poznan and Warsaw (Poland)–pilot study
Magdalena Waszyk-Nowaczyk, Beata Szukalska, Weronika Guzenda, Michał Michalak
WIĘCEJ
Beyond clinical care: the pharmacoeconomic and research roles of pharmacists in Poland
Iga Pawłowska, Natalia Krzyżaniak, Leszek Pawłowski, Ivan Kocić
WIĘCEJ
Antipsychotics and low vitamin D – additional data calling for drug causality assessment
Svetlana Ristic, Dragan Milovanovic, Vladimir Janjic, Marijana Stanojevic Pirkovic, Ivana Simic Vukomanov-ic, Svetlana Curcic, Sanja Kocic
WIĘCEJ
Fermented oriental medicinal insect extract has a synergistic effect on inhibiting TGF-beta1- or H2O2-induced hepatic fibrogenesis in LX-2 and HepG2 cells
Young-Ji Choi, In-Sun Park, You-Kyung Son, Kang-Yeol Yu, Jiyoung Kim, Young-Moo Choo
WIĘCEJ
Applicability of the evidem multi-criteria decision analysis framework for orphan drugs – results from a stydy in 7 Eurasian countries
Aleksandra Baran-Kooiker, Kagan Atikeler, Kamilla Gaitova, Malwina Holownia-Voloskova, Adina Turcu-Stiolica, Coen Kooiker, Oresta Piniazhko, Marcin Czech
WIĘCEJ
How to identify osteoporotic patients’ attitude towards pharmaceutical practice?
Edit Veszelyné Kotán, Zoltán Vincze, Ágne Mészáros
WIĘCEJ
Effects of vitamin D3 and resveratrol on learning and memory disabilities of streptozotocin-induced diabetic mice
Tyrosinase inhibitory and antioxidant activity of wild Rosa canina L. and Sorbus aucuparia L. fruit extracts
Milica I. Stanković, Vesna Lj. Savić, Jelena V. Živković, Ljiljana P. Stanojević, Vanja M. Tadić, Ivana A. Arsić
WIĘCEJ
Dose-effect relationship on anti-inflammatory activity on LPS induced raw 264.7 cells and antioxidant activity of rutin in vitro
Chunlian Tian, Yuru Guo, Yu Chang, Jihang Zhao, Cancan Cui, Mingchun Liu
WIĘCEJ
Cyanidin and peonidin inhibit spca-1 growth in vitro via inducing cell cycle arrest and apoptosis
Heng Yue, Qianqian Xu, Liuzhuang Lv, Hua Fan, Jianfeng Xu, Wenhan Wang
WIĘCEJ
Assessments of antioxidant content and the anti-carcinogenic effect of extracts of Solanum rostratum Dunal in human cancer cells
María del Carmen Valadez-Vega, Jeannett A. Izquierdo-Vega, Manuel Sánchez-Gutiérrez, José Roberto Vil-lagómez-Ibarra, Eduardo Osiris Madrigal Santillán, José A. Morales-González, Mirandeli Bautista-Ávila, Laura García-Velazco
WIĘCEJ
Allium ursinum L. leaves components modified the physico-chemical properties of red blood cells protecting them from the effects of oxidative stress
Sylwia Cyboran-Mikołajczyk, Halina Kleszczyńska, Jan Oszmiański, Robert Pasławski
WIĘCEJ
Synthesis and biological evaluation of some new pyridines, isoxazoles and isoxazolopyridazines bearing 1,2,3-triazole moiety
Huda R.M. Rashdan, Anhar Abdel-Aziem, Dina H. El-Naggar, Sara Nabil
WIĘCEJ
Design, synthesis and biological estimation of innovative pyrazoles as anticancer agents targeting CDK2
Ibrahim Ali M. Radini, Diaa A. Ibrahim, Rizk E. Khidre
WIĘCEJ
Analytical procedure elaboration of total flavonoid content determination and antimicrobial activity of bee bread extracts
Nataliia Hudz, Oksana Yezerska, Olga Grygorieva, Soňa Felsöciová, Ján Brindza, Piotr P. Wieczorek, Miroslava Kačániová
WIĘCEJ
The radiation sterilization of imipenem and cilastatin in the solid state
Karolina Kilińska, Judyta Cielecka-Piontek, Robert Skibiński, Daria Szymanowska, Andrzej Miklaszewski, Waldemar Bednarski, Przemysław Zalewski
WIĘCEJ
Determination of acyclovir in rabbit plasma by high performance liquid chromatographic (HPLC) technique
Nadia Shamshad Malik, Mahmood Ahmad, Muhammad Usman Minhas, Qandeel Khalid
WIĘCEJ
Neuroprotection to counteract glaucomatous degeneration of retina; the use of citicoline
Safety of ombitasvir/paritaprevir/ritonavir+dasabuvir in chronic hepatitis C patients with HCV genotype 1 infection
Tomasz Tatara, Marta Dąbrowska-Bender, Aneta Duda-Zalewska, Anna Staniszewska
WIĘCEJ
Off-label use of medicinal products – legal rules and practices
Janusz Jaroszyński, Aneta Mela, Marzena Furtak-Niczyporuk, Łukasz Poniatowski, Jan Dąbrowski, Anna Czajka-Bełz, Agnieszka Zimmermann, Piotr Dreher, Bartłomiej Drop, Anna Staniszewska
WIĘCEJ
The radiostability of betamipron in the solid state
Karolina Kilińska, Judyta Cielecka-Piontek, Robert Skibiński, Andrzej Miklaszewski, Waldemar Bednarski, Przemysław Zalewski
WIĘCEJ
Approach of the State Pharmacopeia of Ukraine to analytical procedures validation on the example of chloride ions assay in peritoneal dialysis solutions
Nataliia Hudz, Dmytro Leontiev, Piotr P. Wieczorek
WIĘCEJ
Pharmacokinetic interaction after oral coadministration of clarithromycin and the tyrosine kinase inhibitor
lapatinib in rats
Agnieszka Karbownik, Joanna Porażka, Anna Łuczak, Artur Teżyk, Tomasz Grabowski, Anna Wolc,Edmund Grześkowiak, Edyta Szałek
WIĘCEJ
Pegylated gemcitabine and methotrexate: in vitro cytotoxicity analysis and in vivo drug release profiling to assess their enhanced blood circulation
Sumera Noreen, Muhammad Abdul Qadir, Mahmood Ahmed, Syeda Kiran Shahzadi, Muhammad Yousaf
WIĘCEJ
The effect of niclosamide on the head and neck carcinoma cells survival and the expression of Wnt/beta-catenin signaling and glycolysis pathway components
Robert Kleszcz, Jarosław Paluszczak, Wanda Baer-Dubowska
WIĘCEJ
Total phenolic and flavonoid contents, antioxidant and antibacterial activities of selected honeys against human pathogenic bacteria
Jelena Živković, Slavica Sunarić, Nemanja Stanković, Tatjana Mihajilov-Krstev, Ana Spasić
WIĘCEJ
Eucommia ulmoides Oliv. extract regulates ages-induced injury in tubular endothelial cells via the rage-Nrf2 pathway
Jinyoung Hur, Moon Ho Do, Mina Kim, Jiwon Choi, Yoonsook Kim, Sang Keun Ha
WIĘCEJ
Chemical composition, cytotoxic and antioxidant activities of Celosia trigyna L. grown in Saudi Arabia
Samy Korany El-Desouky, Ahmed Awad Abdelgawad, Ali Mohamed El-Hagrassi Usama Wahid Hawas, Young-Kyoon Kim
WIĘCEJ
Cytotoxic activity of Varthemia iphionoides essential oil against various human cancer cell lines
Manal Mohammad Abbas, Manal Ahmad Abbas, Yasser Ibrahim Kandil
WIĘCEJ
Surface-active agents from the group of polyoxyethylated glycerol esters of fatty acids. Part IV. Equilibrium micellar solubilization of selected lipophilic therapeutic agents (BCS class II and III) in aqueous solutions of products
Michał K. Kołodziejczyk, Michał J. Nachajski, Zbigniew Marczyński, Marian M. Zgoda
WIĘCEJ
Development of hydrogel capsules for use in dual-phase topical preparations containing dihydroxyacetone and amino acids – preliminary results
Bianka Jacyna, Barbara Mikolaszek, Bartosz Maciejewski, Krzysztof Cal
WIĘCEJ
Irisflorentin suppresses allergic inflammation in mast cells via reducing histamine release and production of pro-inflammatory
