Arkadiusz Kazula

Interferencja RNA - nowa metoda terapii genowej

RNA interference - a new strategy of gene therapy. RNA interference is a remarkable type of gene regulation based on sequence-specific targeting and degradation of RNA. The term encompasses related pathways found in a broad range of eukariotic organisms, inducing humans. RNAi technology is currently being evaluated not only as an extremely powerful instrument for functional genomic analyses, but also as a potentially useful method to develop specific dsRNA-based gene-silencing therapeutics. RNA-based strategies for gene inhibition in mammalian cells have recently been described, which offer the promise of antiviral and cancer therapy.