TABLE OF CONTENTS

Rok
Lista numerów

The effect of pH on cyclodextrin complexation of trifluoperazine.

Anna Lutka, Bartosz Gołda WIĘCEJ

A simpler and faster capillary electrophoresis method for determination of mianserin enantiomers in human serum.

Błażej Grodner, Jan Pachecka WIĘCEJ

Topoisomerase II alpha expression and cytotoxicity of anthracyclines in human neoplastic cells.

Beata M. Gruber, Elżbieta L. Januszewska, Iza Roman, Aneta Goüdzik, Waldemar Priebe, Izabela Fokt WIĘCEJ

Preliminary evaluation of antioxidant activity of some 1-( phenoxyethyl)-piperazine derivatives.

Agata Pietrzycka, Marek StÍpniewski, Anna M. Waszkiewicz, Henryk Marona WIĘCEJ

Synthesis and pharmacological evaluation of 2-hydroxy-methylbenzamides as anti-inflammatory and analgesic agents.

Lucky O. Okunorobo, Cyril O. Usifoh, Gerhard K. E. Scriba WIĘCEJ

Synthesis of alkylamides of dipeptides as potential plasmin inhibitors.

Krystyna Midura-Nowaczek, Izabela Lepietuszko, Irena Bruzgo WIĘCEJ

Studies on pyrazine derivatives. XLVII. Synthesis and antibacterial activity of novel pyrazine derivatives with amidoxine moiety.

Katarzyna Gobis, Henryk Foks, Anna KÍdzia, Maria Wierzchowska, Ewa Kwapisz, Zofia Zwolska, Ewa Augustynowicz-Kopeć WIĘCEJ

Synthesis of amides of 5-arylidene-2,4-dioxothiazolidine-3-acetic acid with 1,2,4-triazole system.

Nazar Trostko, Maria Dobosz, Victor Lukinchuk WIĘCEJ

Formulation and evaluation of floating drug delivery system containing clarithromycin for helicobacter pylori.

Sanjay S. Patel, S. Ray, R. S. Thakur WIĘCEJ

In vitro dissolution kinetic study of theophylline from hydrophilic and hydrophobic matrices.

Hamzah M. Maswadeh, Mohammad H. Semreen, Abdulatif A. Abdulhalim WIĘCEJ

Influence of acrylic esters and methacyrlic esters on flotation of pellets and release rate of verapamil hydrochloride.

Rafał Łunio, Wiesław Sawicki WIĘCEJ

Artificial neural networks in the modelling of drugs release profiles from hydrodynamically balanced system.

Aleksander Mendyk, Renata Jachowicz, Przemysław Dorożyński WIĘCEJ

Exploring effects of different nonsteroidal antiinflammatory drugs on malondialdehyde profile.

Santanu Chakraborty, Sudip Kumar Kar, Kunal Roy, Chandana Sengupta WIĘCEJ

The alkoxyacetic acids as calcium and magnesium chelating agents in vitro.

Andrzej Starek, Piotr Nowak WIĘCEJ

Synthesis, characterization, antibacterial and cytotoxicity studies on some mixed ligand Th(IV) complexes.

Ganesh A. Thakur, Manzoor M. Shaikh WIĘCEJ

Synthesis and anticonvulsant properties of new N-phenylamino derivatives of 2-azaspiro[4,4]nonane, 2-azaspiro[4.5]decane-1,3-dione and 3-cyclohexylpyrrolidine-2,5-dione. Part IV.

Jolanta Obniska, Krzysztof Kamiński WIĘCEJ

Cardiac glycosides in cancer research and cancer therapy.

Katarzyna Winnicka, Krzysztof Bielawski, Anna Bielawska WIĘCEJ

Aqueous ginger extract ameliorates paraben induced cytotoxicity.

Venna Asnani, Ramtej Jayram Verma WIĘCEJ

The presence of microorganisms in some common excipients used in tablet formulation.

Ifeyinwa F. Obuekwe, Florence Eichie WIĘCEJ

The effect of saccharic alkohols on rheological parameters of dental anti-inflammatory gels and on pharmaceutical availability of sodium ibuprofen.

Justyna Kołodziejska WIĘCEJ

Solubility of selected derivatives of 1,4-benzodiazepin-2-one in solid dispersions in PEG 6000.

Barbara Ćwiertnia WIĘCEJ

Evaluation of zidovudine encapsulated ethylcellulose micro- sheres prepared by water-in-oil-in-oil (w/o/o) double emulsion solvent diffusion technique.

Malay Kumar Das, Kalakuntala Rama Rao WIĘCEJ

Effect of e-aminocaproylaminoacids of fibrin formation.

Irena Bruzgo, Krystyna Midura-Nowaczek, Magdalena Bruzgo, Joanna Kaczyńska, Wiesława Roszkowska-Jakimiec WIĘCEJ

The urothelium cell culture on the starch scaffold.

Tomasz Drewa WIĘCEJ

A comparison of theoretical methods of calculation of partition coefficients for selected drugs.

Alina Pyka, Magdalena Babuúka, Magdalena Zachariasz WIĘCEJ

Determination of metoprolol and hydrochlorothiazide by derivative spectrophotometric method in pharmaceutical preparations.

Marusz Stolarczyk, Radosław Ekiert, Jan Krzek,Włodzimierz Rzeszutko WIĘCEJ

An HPLC Method for the indirect quantification of a quinone adduct of the drug paroxetine.

Janusz Łukowski, Duncan Bryant, Patrick Camilleri WIĘCEJ

Differential inhibitory effect of newly synthesized pyridine-2- one derivatives on the cercarial serine protease activity of the parasite schistosoma mansoni.

Mahmoud Bahgat, Nagy Khalifa WIĘCEJ

Anti-inflammatory and gastroprotective properties of some chalcones.

Krystyna PorÍba, Joanna Wietrzyk, Adam Opolski WIĘCEJ

Ring opening of 1-phthaloylimido-[4-(2-methoxyphenyl) piperazin- 1-yl] alkyl derivatives: synthesis, analgesic and antiinflammatory properties of products.

Lucky O. Okunrobo, Cyril O. Usifoh, John O. Uwaya WIĘCEJ

Crystallization of a non-steroidal anti-inflammatory drug from ethanol-water solution in presence of polymers: physicoche mical characterization and release behaviour from suppositories.

Lucky O. Okunrobo, Cyril O. Usifoh, Avishen Mitra WIĘCEJ

Phenolic acids in the flowers of Althea rosea var. nigra.

Marlena Dudek, Irena Matrtawska, Maurycy Szkudlarek WIĘCEJ

Antimutaganic and antioxidantt activity of the extract from Belcamcanda chinensis (L.) DC.

Dorota Woźniak, Jan Oszmiański, Adam Matkowski WIĘCEJ

Steroidal gycosides from the underground parts of Alliumursinum L. and their cytostatic and antimicrobial activity.

Danuta Sobolewska, Zbigniew Janeczko, Wanda Kisiel, Irma Podolak, Agnieszka Galanty, Danuta Trojanowska WIĘCEJ

nfluence of additives and storage temperature on physicochemical and microbiological properties of eye drops containing cefazolin.

Anna Kodym, Tomasz Zawisza, Kamila Buźka, Helena Kukuła WIĘCEJ

solation and characterization of 3-carbomethoxypyridine from the lea leaves of pyrenacantha studtii hutch and dalz (icacinaceae).

Abiodun Falodun, Cyril O. Usifoh WIĘCEJ

Ketoprofen ion-selective electrode and its application to pharmaceutical analysis.

Joanna Lenik, Cecylia Wardak, Barbara Marczewska WIĘCEJ

Synthesis and properties of 4-alkoxy-2-[2-hydroxy-3-(4-o,m,p-halogenoaryl-1-piperazinyl)propyl]-6-methyl-1H-pyrrolo-[3,4-c] pyridine-1,3(2H)-diones with analgesic and sedative activities.

Helena Śladowska, Aleksandra Sabiniarz, Dominika Szkatuła, Barbara Filipek, Jacek Sapa WIĘCEJ

Synthesis of new 1-(amino)-3-[1,5-diphenyl-1H-1,2,4-triazol-3- yl)oxy] propan-2-ol and 1-[(1,5-diphenyl-1H-1,2,4-triazol-3-yl)oxy]-3-(4-arylpiperazin-1-yl) propan-2-ol derivatives with an expected pS-adrenolytic activity.

Jerzy Kossakowski, Marta Struga, Anna E. Kozioł WIĘCEJ

Synthesis of amino derivatives of 10-(diphenylmethylene)-4- azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione as potential psychotropic and/or anti HIV agents.

Jerzy Kossakowski, Anna Wojciechowska, Anna E. Kozioł WIĘCEJ

Synthesis and serological interactions ofH. pylori urease fragment 321-339 N-terminally immobilized on the cellulose.

Beata Kolesińska, Sebastian Grabowski, Wiesław Kaca, Zbigniew J. Kamiński WIĘCEJ

Synthesis of new derivatives of 2,3-dihydro-7-benzo[b]furanol with potential pharmacological activity.

Jerzy Kossakowski, Kinga Ostrowska WIĘCEJ

Anti-inflammatory activity of Achillea and Ruscus topical gel on carrageenan-induced paw edema in rats.

Hamzah M. Maswadeh, Mohammad H. Semreen, Ahmad R. Naddaf WIĘCEJ

Comparative study of phenolic acids in pseudofruits of some species of roses.

Renata Nowak WIĘCEJ

Determination of ellagic acid in pseudofruits of some species of roses.

Renata Nowak WIĘCEJ

Physicochemical and microbiological properties of eye drops containing cefuroxime.

Anna Kodym, Tomasz Zawisza, Joanna Taberska, Helena Kukuła WIĘCEJ

Raloxifene does not affect the changes in bone histomorphometric parameters induced by low dose tacrolimus in male rats.

Ilona Kaczmarczyk-Sedlak, Joanna Folwarczna, Urszula Cegieła, Barbara Nowińska, Maria Pytlik, Waldemar aniec, Leszek Śliwiński WIĘCEJ

Black tea ameliorates aflatoxin-induced lipid peroxidation in the kidney of mice.

Anamika Choudhary, Ramtej Jayram Verma WIĘCEJ

The FAS-related apoptosis signaling pathway in the prostate intraepithelial neoplasia and cancer lesions.

Tomasz Drewa, Zbigniew Wolski, Zdzisław Skok, Rafał Czajkowski, Halina Wiśniewska WIĘCEJ

Flavonoid aglycones and phytosterols from the Erigeron acris L. herb

Jolanta Nazaruk WIĘCEJ

Estimation of DNA damage and cytotoxicity of anthracycline analogs in human melanoma cells on early and late passages

Elżbieta Anuszewska, Bożena Chłopkiewicz, Beata Gruber, Jadwiga Marczewska, Waldemar Priebe, Henryk Skurzak WIĘCEJ

Editorial.

Professor Grzegorz Grynkiewicz WIĘCEJ

Molecular medicine of the future - applications and pitfalls.

Jerzy Ostrowski WIĘCEJ

Asymetric syntheses and transformations - tools for chirality multiplication in drug synthesis.

Jacek Gawroński WIĘCEJ

Biodegradable nano- and microparticles as carriers of bioactive compounds.

Stanisław Słomkowski WIĘCEJ

New targets for putative neuroprotective agents.

Danuta Jantas-Skotniczna, Małgorzata Kajta, Władysław Lasoń WIĘCEJ

Cancer chemopreventive agents - drugs for the 21st century?

Wanda Baer-Dubowska WIĘCEJ

Synthesis and antibacterial activity of 5-adamantan-1-yl-methyl analogues of trimethoprim.

Barbara Orzeszko, Michał Fedoryński, Agnieszka Ewa Laudy, Bohdan Jerzy Starościak, Andrzej Orzeszko WIĘCEJ

The biological activity of new tuftsin derivatives - induction of phagocytosis.

Anna Wardowska, Krystyna Dzierzbicka, Piotr Trzonkowski, Andrzej Myśliwski WIĘCEJ

Biotransformation of praziquantel by human cytochrome P450 3A4 (CYP 3A4).

Anna Godawska-Matysik, Katarzyna Kieć-Kononowicz WIĘCEJ

The influence of simvastatin at high dose and diltiazem on myocardium in rabbits, the biochemical study.

Magdalena Jasińska, Jacek Owczarek, Daria Orszulak-Michalak WIĘCEJ

Determination of impurities in pharmaceutical preparations containing folic acid.

Gabriela Kłaczkow, Elżbieta L. Januszewska WIĘCEJ

Drug-related hospital admissions - an overview of frequency and clinical presentation.

Dorota Jenerowicz, Magdalena Czarnecka-Opieracz, Alina Górecka, Maciej Stawny WIĘCEJ

Optimization of chiral separation of pramipexole on various polisaccharide stationary phases.

Agata E. Kamieńska-Duda, Piotr A. Baran, Anna Bielejewska, Michał Odrowąż-Sypniewski WIĘCEJ

Identification and determination of angiotensin II receptor antagonists with densitometric method.

Krystyna Czerwińska, Aleksander Mazurek WIĘCEJ

Determination by chromatographic methods of selected madicines reducing the level of cholesterol.

Elżbieta Kublin, Barbara Kaczmarska-Graczyk, Aleksander P. Mazurek WIĘCEJ

Fluorometric detection of aldehyde dehydrogenase activity in human saliva in diagnostic of cancers of oral cavity.

Piotr Wroczyński, Jolanta Giebułtowicz, Janusz Piekarczyk, Jacek Wierzchowski WIĘCEJ

Simultaneous determination of midazolam and its a-hydroxy metabolite in human plasma by LC-MS using an automatic solid-phase extraction system.

Kamila Kobylińska, Agata Sarosiek, Julita Kuczyńska WIĘCEJ

Validation of analytical procedure - control of residual ethanol, 2-propanol and ethyl acetate in pharmaceutical substance - imatinib.

Aleksandra Groman, Piotr Gołębiewski WIĘCEJ

Validated LC-MS method for determination of tamsulosin in human plasma and its application to pharmacokinetic study.

Hanna Ksycińska, Piotr J. Rudzki, Agata Sarosiek WIĘCEJ

Investigation on the synthesis and properties of 2-(alkyl,aryl)-1,4,5-trioxo-1,2,3,4,5,6-hexahydropyrido[3,4-d]pyridazines, derivatives with potential biological activity.

Jakub Stanasiuk WIĘCEJ

Synthesis of 1-aminomethyl derivatives of 3-benzyl-4-ethyl-1,2,4-triazoline-5-thione.

Monika Pitucha, Monika Wujec, Maria Dobosz WIĘCEJ

ynthesis of some N-substituted derivatives of 1-(1h-pyrrole-1-ylmethyl)-10-oxa-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione with an expected anxiolytic activity.

Jerzy Kossakowski, Magdalena Pakosińska-Parys WIĘCEJ

An approach to enantioselective activation of N-benzoyl-a-methylserine with chiral N-triazinylammonium chloride.

Beata Kolasińska, Toshifumi Miyazawa, Janina E. Kamińska, Sebastian Olczyk, Zbigniew J. Kamiński WIĘCEJ

Unnatural d-amino acids as building blocks of new peptidomimetics.

Gniewomir Latacz, Elżbieta Pękala, Agnieszka Ciopińska, Katarzyna Kieć-Kononowicz WIĘCEJ

Synthesis and antiproliferation activity of the products obtained in the reaction of N3-substituted amidrazones from 1,2-cyclohexanedicarboxylic anhydride.

Bożena Modzelewska-Banachiewicz, Wojciech Rzeski, Alicja Nowaczyk, Marzena Ucherek WIĘCEJ

Clustering as a supporting tool for structural drug design.

Dominik Gront, Mateusz Kurciński, Andrzej Koliński WIĘCEJ

Simvastin intensifies heart rate depression after metoprolol and atropine administration in normocholesterolemic rats.

Jacek Owczarek, Magdalena Jasińska, Irena Wejman, Magdalena Baryś, Daria Orszulak-Michalak WIĘCEJ

Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines.

Arkadiusz Orchel, Arkadiusz Gruchlik, Ludmiła Węglarz, Zofia Dzierżewicz WIĘCEJ

Anti-proliferative effects of inositol hexaphosphate and verapamil on human colon cancer Caco-2 and HT-29 cells.

Ludmiła Węglarz, Beata Parfiniewicz, Arkadiusz Orchel, Zofia Dzierżewicz WIĘCEJ

Antoxid increases ferric reducing antioxidant (frap) even stronger than vitamin C.

Anna Długosz, Jadwiga Lembas-Bogaczyk, Eliza Lamier-Zarawska WIĘCEJ

The influence of antoxid on chemically induced lipid peroxidation.

Dorota Piotrowska, Anna Długosz, Dorota Przybylska, Adam Matkowski WIĘCEJ

The incidence of jaw osteonecrosis in multiple myeloma patients treated with bisphosphonates.

Maria Kraj, Ryszard Pogłód, Stanisław Maj, Katarzyna Owczarska WIĘCEJ

The efficacy and safety of brtezomib (VelcadeN) in the tretment of relapsed multiple mye.

Krzysztof Warzocha, Maria Kraj, Ryszard Podłóg, Urszula Sokołowska WIĘCEJ

Growth of human chondrocytes on biodegradable synthetic polymers.

Arkadiusz Orchel, Katarzyna Jelonek, Janusz Kasperczyk, Izabella Molin, Joanna Wawszczyk, Ludmiła Węglarz, Ireneusz Bielecki, Zofia Dzierżewicz WIĘCEJ

Estimation of antimicrobal activity of selected non-antibiotic products.

Hanna Kruszewska, Tomasz Zaręba, Stefan Tyski WIĘCEJ

Antimicrobal activities of 4-substituted-3-(piperidin-4-yl}-4,5-dihydro-1h-1,2,4-triazole-5-thiones.

Urszula Kosikowska, Agata Siwek, Maria Dobosz WIĘCEJ

Submerged cultivation of Streptomyces tsukubaensis in media composed of waste products of food industry.

Jadwiga Turło, Bożena Gutkowska, Wanda Gajzlerska WIĘCEJ

Validation of HPLC method for determination of atorvastatin in tablets and for monitoring stability in solid phase.

Beata Stanisz , Łukasz Kania WIĘCEJ

Thermal stability of 1,4-dihydropyridine derivatives in solid state.

Barbara Marciniec, Magdalena Ogrodowczyk WIĘCEJ

Synthesis of oxiran-2-ylmethyl and oxiran-2-ylmethoxy derivatives of some 4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-diones as potential beta-adrenolytics.

Jerzy Kossakowski, Anna Wojciechowska WIĘCEJ

Synthesis and antimicrobial activity of 3-(4í-hydroxy-3í-methylphenyl)-5-[(substuted) phenyl]-4,5-dihydro-1H-1-pyrazolyl-4- pyridylmethanone derivatives.

Mohammad Shahar yar, Mohamed Ashraf Ali, Dharmarajan Sriram, Perumal Yogeeswari WIĘCEJ

Analysis of aqueos extract of Inonotus obliquus.

Witold Mazurkiewicz WIĘCEJ

Evaluation of purity of certain pediatric preparations of plant origin and its significance for the safety of pharmacotherapy. Microbiological contamination of pediatric preparations of plant origin.

Barbara Figura, Janusz Pluta WIĘCEJ

Influence of additives and storage temperature on physicochemical and microbiological properties of eye drops containing ceftazidime.

Anna Kodym, Tomasz Zawisza, Beata Napierała, Helena Kukuła WIĘCEJ

In vitro investigation of sodium diclofenac adsorption on sucralfate.

Bożena Grimling, Janusz Pluta WIĘCEJ

Preparation and evaluation of modified release ibuprofen microspheres with acrylic polymers (Eudragit) by quasi-emulsion solvent diffusion method: effect of variables.

Burcu Devrim, Kandemir Canefe WIĘCEJ

Effect of penetration enhancers on skin permeation of trazodone hydrochloride from matrix type transdermal formulation through mouse and human cadaver epidermis.

Malay K. Das, Asokangshu Bhattacharya, Saroj K. Ghosal WIĘCEJ

The influence of staphylococcin T (StT) on the mouse fibroblasts (3T3) viability, an in vitro experiment

Tomasz Drewa, Agnieszka Krawczyk,Eugenia Gospodarek, Katarzyna Jachna-Sawicka,Roman Bugalski, Celestyna Kierzenkowska-Mila WIĘCEJ

Effect of Vita Glucan on some antioxidant parameters of the human blood. In vitro study.

Agata Pietrzycka, Marek StÍpniewski,Anna M. Waszkielewicz, Henryk Marona,Agata Krzyżanowska, Katarzyna Ktosowska, Olaf Solarz WIĘCEJ