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Metformin - from anti-diabetic drug to anti-cancer drug

Magdalena Markowicz-Piasecka, Kristiina M. Huttunen, Elżbieta Mikiciuk-Olasik, Łukasz Mateusiak Joanna Sikora WIĘCEJ

Determination of nifedipine by reverse phase high performance liquid chromatography in rabbit plasma.

Rabia Razzaq, Nazar Mohammad Ranjha, Rehmana Rashid, Zermina Rashid Zhanting Yang, Ming Chen, Yuhao Zhang, Dejun Zhang WIĘCEJ

Analysis of the constituents in rat serum after oral administration of ethyl acetate extract of the tibetan herbal medicine Oxytropis falcata by HPLC-MS.

Wangtao Yuan, Ping Shi, Benyin Zhang, Eun-Kyung Hong WIĘCEJ

Antioxidative properties of human insulin reference material and rapid-acting and long-acting insulin analog standards.

Katarzyna Komosińska-Vassev, Paweł Olczyk, Paweł Ramos, Łukasz Mencner, Krystyna Olczyk, Barbara Pilawa WIĘCEJ

Studies on the antioxidant and xanthine oxidase inhibition potential of Heliotropium crispum.

Muhammad Adeel Arshad, Saeed Ahmad, Umair Khurshid, Irfan Pervaiz WIĘCEJ

Effects of the CYP3a4 genetic polymorphisms on the analgesic efficacy of fentanyl in adults: a meta-analysis.

Shujun Lu, Wenli Yu, Yajing Zhang, Hongyin Du, Minzhu, Shaoting Yuan WIĘCEJ

Viability and apoptotic effects of green tea (Camellia sinensis) methanol extract on human leukemic cell lines.

Norazrina Azmi, Chee Sze Hui, Norsyahida Mohd Fauzi, Malina Jasamai, Endang Kumolosasi WIĘCEJ

Synthesis and biological activity of pyrimidines, quinolines, thiazines and pyrazoles bearing a common thieno moiety

Ameen Ali Abu-Hashem WIĘCEJ

Identification of secondary metabolites and resistance modifying activity of Ficus bizanae leaf, stem bark and fruit extracts.

Gbonjubola V. Awolola, Hafizah Y. Chenia, Himansu Baijnath, Neil A. Koorbanally WIĘCEJ

Oxalate, calcium and magnesium content in Melissa officinalis L. and Equisetum arvense L. infusions.

Elżbieta Królak, Elżbieta Biardzka, Karolina Gałgan WIĘCEJ

Effect of alcoholic extract of Adhatoda vasica L. leaves and Allium cepa L. bulb in diabetic wound healing in Wistar albino rats.

Nidhi S. Patel, Viren N. Naik, Hiren N. Hirapara, Hemangini R. Acharya, Seema N. Baxi, Chandrab-hanu Tripathi WIĘCEJ

Non-invasive in vivo evaluations of cosmetic emulsion containing phytoextract of grape seeds in the treatment of skin aging by using non-invasive bio-engineering techniques.

Muhammad Khurram Waqas, Naveed Akhtar, Akhtar Rasul, Ayesha Sethi, Khizar Abbas, Talib Hussain WIĘCEJ

Assessment of sustained release matrix tablets for quetiapine fumarate: in-vitro studies.

Sadia Urooj, Atif Ali, Hira Khan, Sajid Hussain Shah, Muhammad Hassham Hassan Bin Asad, Fatima Rasool, Muhammad Shoaib Khan, Naheed Akhtar, Abdul Wahaab WIĘCEJ

Development and evaluation of matrix patches as transdermal drug delivery system for amlodipine.

Muhammad Asad Abrar, Mahmood Ahmad, Muhammad Rouf Akram WIĘCEJ

Fortification of facial skin collagen efficacy by combined ascorbyl palmitate and sodium ascorbyl phosphate.

Hira Khan, Naveed Akhtar, Atif Ali WIĘCEJ

Thermosensitive in situ gel formulation containing plga nanoparticles of flurbiprofen for ocular delivery.

Eda Aydin, Ulya Badilli, Arzu Onay-Besikci, Nilufer Tarimci WIĘCEJ

Ball mill based co-milling: a promising way to enhance aqueous solubility of poorly soluble drugs employing norfloxacin as model drug.

Maria Mir, Khezar Hayat, Talib Hussain, Muhammad Khurram Waqas, Nadeem Irfan Bukhari WIĘCEJ

The effect of polymer properties on the release mechanisms of diclofenac sodium from controlled release ma-trix tablets.

Łukasz Zimmer, Regina Kasperek, Agnieszka Kierys, Marta Grochowicz, Ewa Poleszak WIĘCEJ

Dexmedetomidine infusion prevents significant postoperative pain in the first 24 hours after myomectomy laparoscopic surgery.

Bushra Abdul Hadi, Saleh M. Sbeitan, Ashok K. Shakya WIĘCEJ

The effect of vehiculum and age on serum chlorzoxazone concentration in the rat.

Marcin Łukasik, Anna Małkowska, Magdalena Bamburowicz-Klimkowska, Mirosław M. Szutowski WIĘCEJ

The use of intravenous fish oil in neonates: current clinical practices.

Magdalena Piętka, Dominika Stepska, Anna Przybyło, Anna Kowalik, Magdalena Kryjak, Witold Brniak, Stanisław Klek WIĘCEJ

Effects of single injection of naloxone and damgo within nucleus accumbens septi in the plus maze test in rats.

Cristian Morsucci, Ainura Okasova, Daniela Mulet, Graciana Galiana, Vanesa Rodríguez, Gustavo C. Baiardi, José Vicente Lafuente, Pablo Adolfo Elías, Adriana I. Landa, Marta Soaje, Pascual A. Gargiulo WIĘCEJ

Sildenafil, a selective phosphodiesterase 5 inhibitor, down-regulates natural killer cells activity in healthy men in vitro.

Agnieszka Boguska, Beata Kaleta, Monika Kniotek, Andrzej Górski WIĘCEJ

Quantitative study of pharmaceutical care services in Khyber Pakhtunkhwa province, Pakistan: physi-cians’ perception.

Saira Azhar, Rozina Kousar, Shujaat Ali Khan, Ghulam Murtaza WIĘCEJ

Analysis of pharmacotherapy in senior homes residents.

Jozef Kolar, Barbora Tinkova, Tünde Ambrus, Veronika Tinkova WIĘCEJ

Community pharmacists’ use in cancer care of Hungary and Germany – a comprehensive evaluation of a pa-tient intended questionnaire complemented with estimations of professional health experts.

Johannes Thoma, Romána Zelkó, Balázs Hankó WIĘCEJ

Restrictions on the advertising of medicinal products in Poland and violations thereof from 2011 to 2015.

Aleksandra Czerw, Aleksandra Siuchta, Anna Augustynowicz, Grażyna Dykowska, Rafał Szpakowski, Anna Staniszewska WIĘCEJ

Stimation of ten illicit drugs abuse in Hangzhou through sewage-based analysis.

Zhigang Zhou, Yi Wang, Haixia Yu, Zhi Zhang, Jialing Wang, Hongru Lv WIĘCEJ

Cytotoxic properties of selected derivatives of benzofurans - preliminary studies.

Mariola Napiórkowska, Silvia Madeddu, Gabriele Giliberti, Giuseppina Sanna WIĘCEJ

Synthesis, characterization and in vitro biological screening of triphenyltin derivatives of isoniazid hydrazine.

Mohsin Abbas Khan, Samar Akhtar, Khadija Shahid, Syed Aun Muhammad, Amara Mumtaz, Mu-hammad Arfat Yameen, Nighat Fatami WIĘCEJ

Pełna wersja czasopisma/The entire magazine

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Echoes from the past:Professor Witold Rawita-Witanowski, 1899-1945, biochemist, neurophysiologist, and pharmacologist, first editor of Acta Poloniae Pharmaceutica

Joanna Witanowska, Piotr Wroczyński WIĘCEJ

Present-day toxicity of smoke inhalation

Monika Rużycka, Joanna Giebułtowicz, Piotr Wroczyński WIĘCEJ

A history of the physical and chemical stability of pharmaceuticals – a review

Marzena Jamrógiewicz, Martyna Merchel WIĘCEJ

Antihypertensive medicines mixture analysis in blood plasma using chromatographic methods

Lukas Valintelis, Mindaugas Marksa, Andrejus Zevzikovas, Augusta Zevzikoviene, Vaidas Skyrius WIĘCEJ

In vivo research of cosmetic forms containing -carotene

Joanna Igielska-Kalwat, Tariq Mahmood WIĘCEJ

The influence of micellar system on antioxidant activity of common terpenoids measured by uv-vis spectropho-tometry

Karolina Wojtunik-Kulesza, Łukasz Cieśla, Anna Oniszczuk, Monika Waksmundzka-Hajnos WIĘCEJ

Screening the anticancer drugs against Cys2His2 of human DPF2 using isothernal titration calorimetry and fluorescence quench

Ming Lei, Hui Zhang, Zhijuan Zhao, Ke Liu, Yixuan Hu, Kashif Rafiq Zahid, Yanli Liu, Jihong Yang, Haobin Zhao, Yi Yang, Chao Qi i WIĘCEJ

Vibrational spectroscopic (FT-IR, Raman) investigations and theoretical studies of some crystalline ce

Przemysław Zalewski, Kornelia Lewandowska, Bolesław Barszcz, Mikołaj Mizera, Szymon Sip, Piotr Garbacki, Gabriela Wiergowska, Judyta Cielecka-Piontek WIĘCEJ

5-(3-Pyridinyl)thiazole[4,5-d]pyrimidine derivatives: synthesis and in vitro anticancer evaluation

Lilianna Becan, Anna Wójcicka WIĘCEJ

Microwave enhanced synthesis of biocompelling substituted oxa/thiazoles via acetyl coumarin azomethine

Erum Akbar Hussain, Narjis Naz, Ambreen Ghani, Abida Yasmeen, Sobia Ishaque WIĘCEJ

Efficient synthesis and molecular modeling of new N-/S-nucleosides and schiff’s bases of tetrahydropyrimidine scaffold as potential H5N1 avian influenza a virus inhibitors

Eman R. Kotb, Hemat S. Khalaf, Yasmin M. Syam, Ola Bagato, Mwafia A. Salama WIĘCEJ

Aminobenzoic acid derivatives as antioxidants and cholinesterase inhibitors; synthesis, biological evaluation and molecular docking studies

Kiran Iftikhar, Shahzad Murtaza, Naghmana Kousar, Aadil Abbas, Muhammad Nawaz Tahir WIĘCEJ

Synthesis and in vitro antiproliferative activity of novel Mannich bases – 2-arylideneaminobenzimidazoles derivatives

Anna Nowicka, Wanda P. Nawrocka, Hanna Liszkiewicz, Joanna Wietrzyk, Artur Anisiewicz, Wojciech Kołodziejczyk WIĘCEJ

A randomized clinical trial of the effect of a suppository formulation of Nigella sativa on vaginal candidiasis

Nafiseh Saghafi, Behnaz Soiezi, Leila Pourali, Ahmad Ghorbani, Hassan Rakhshandeh WIĘCEJ

New findings of the effect of Wisteria floribunda lectin on gastric cancer cells

Iwona Radziejewska, Edyta Andrulewicz, Małgorzata Borzym-Kluczyk, Joanna Wosek, Łukasz Szoka, Anna Bielawska, Anna Galicka WIĘCEJ

Anti-inflammatory properties of Cantharellus cibarius from in vitro culture enriched in zinc

Joanna Gdula-Argasińska, Agata Grzywacz, Agata Krakowska, Włodzimierz Opoka, Bożena Muszyńska WIĘCEJ

Quantitative analysis of the major constituents of Psoralea corylifolia L. from different cultivation areas by HPLC-MS

Chenghao Fei, Lin Li, Tuling Lu, Weidong Li, Baochang Cai, Fangzhou Yin. WIĘCEJ

Short-term in vitro exposure to crocetin promotes apoptosis in human leukemic HL-60 cells via intrinsic path-way

Maliheh Moradzadeh, Alijan Tabarraei, Ahmad Ghorbani, Azar Hosseini, Hamid R. Sadeghnia WIĘCEJ

Fabrication and characterization of pH-responsive polyethylene glycol 8000-co-poly(methacrylic acid) polymeric composites for treatment of colorectal cancer

Kashif Barkat, Mahmood Ahmad, Muhammad Usman Minhas, Ikrima Khalid WIĘCEJ

Impact of sterilisation conditions on the rheological properties of thermoresponsive pluronic F-127-based gels for the ophthalmic use

Jakub Burak, Kamil P. Grela, Janusz Pluta, Bożena Karolewicz, Dominik M. Marciniak WIĘCEJ

Assessment of in vitro release of calcium from some selected supplements

Aneta Ostróżka-Cieślik, Barbara Dolińska, Florian Ryszka WIĘCEJ

Formulation development and characterization of diphenhydramine nasal nanogel

Hina Javed, Syed Nisar Hussain Shah, Muhammad Mazhar Ayaz, Nida Javed, Furqan Muhammad Iqbal, Muqeet Wahid, Mahtab Ahmad, Ghulam Murtaza WIĘCEJ

Impact of rabeprazole sodium on pharmacokinetics of nimesulide in healthy volunteers: a prospective study from

Iqra Munir, Bilal Aslam, Rana Dawood Naseer, Asif Mahmood, Uzma Saleem, Aisha Sultana, Saiqa Muneer, Muhammad Asad Abrar, Mudassar Ashraf WIĘCEJ

Blood pressure profile and effects of antihypertensive medicatio

Jelena M. Vuckovic-Filipovic, Srdjan M. Milanov, Ivan V. Cekerevac, Violeta M. Iric-Cupic, Marko C. Vuleta, Ivan B. Simic, Vladimir Lj. Jakovljevic, Vladimir I. Zivkovic, Goran T. Davidovic WIĘCEJ

Evaluation of antiplatelet activity of novel guanidine derivatives in the aspects of their adrenergic receptor activity

Agnieszka Zagórska, Monika Marcinkowska, Joanna Śniecikowska, Adam Bucki, Agata Siwek, Monika Kubacka, Grzegorz Kazek, Jacek Sapa, Magdalena Kotańska, Marcin Kołaczkowski WIĘCEJ

Comparison of anticoagulant effect of selected polyphenols

Michał Bijak, Joanna Saluk, Paweł Nowak WIĘCEJ

Access to opioid analgesics in Poland – a brief analysis of he current regulation of opioids following recent legislative changes

Iga Pawłowska, Aleksandra Modlińska, Leszek Pawłowski, Natalia Krzyżaniak, Ivan Kocić, Monika Lichodziejewska-Niemierko WIĘCEJ

The impact of chronic obstructive pulmonary disease (COPD) comorbidities on prognosis and severity of the disease

Edyta Rysiak, Ilona Zaręba, Izabela Prokop, Robert Mróz WIĘCEJ

Self-medication with OTC drugs during the flu or influenza among the residents of Warsaw. Sources of knowledge and awareness of dangers generated by inappropriate treatment

Anna H. Bąk, Magdalena Makarewicz-Wujec, Małgorzata Kozłowska-Wojciechowska WIĘCEJ

Erratum

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Pełna wersja czasopisma/The entire magazine

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Using QALY indicator in oncology on the example of chosen countries

Wojciech Giermaziak, Katarzyna Głowala, Dorota Ubysz, Anna Królak WIĘCEJ

Influence of acid-base properties of selected flavones on their ability to form complexes with iron(ii)

Cecylia Mielczarek, Elżbieta Brzezińska, Dorota Kusztal WIĘCEJ

Development of methods for determining excipients in cholesterol lowering drugs

Elżbieta Kublin, Ewa Malanowicz, Anna Zajączkowska, Krystyna Czerwińska, Elżbieta Wyszomirska, Aleksander P. Mazurek WIĘCEJ

Application of ion pair RP–HPCL method in pharmaceutical quality control dissolution testing for simultaneous estimation of combined tablet dosage forms with acetylsalicylic acid and glycine

Małgorzata Kowalska, Magdalena Woźniak, Michał Kijek, Monika Krawczyk, Sławomir Janas WIĘCEJ

Synthesis and antibacterial activity of Tb(III), Ho(III), Er(III) and Yb(III) complexes of chrysin-4'-sulfonate

Janusz Pusz, Elżbieta Pieniążek, Elżbieta Woźnicka, Ewa Ciszkowicz, Katarzyna Lecka-Szlachta, Stanisław Wołowiec, Łukasz Byczyński WIĘCEJ

Design, synthesis and biological evaluation of novel benzo[4,5]thiazolo[2,3-c][1,2,4]triazole derivatives as potential anticancer agents

Ahmed H. Abdelazeem, Ahmed M. Gouda, Hany A. Omar, Majed Alrobaian WIĘCEJ

Insights into mycobacterial activity and cytotoxicity ofsubstitued isoxazole-4-carbohydrazide derivatives

Paulina Płoszaj, Adam Junka, Bogumiła Szponar, Marcin Mączyński, Stanisław Ryng, Marzenna Bartoszewicz, Agnieszka Piwowar WIĘCEJ

Substituted carboxamide analogues as a new class of local anesthetic agents: synthesis and bio-evaluation

Faisal Al-Otaibi WIĘCEJ

Synthesis and study of substituted amides of some 5-membered isocyclic and heterocyclic acids as potential anticonvulsants

Marzanna Strupińska, Bartłomiej Jakubowicz, Grażyna Rostafińska-Suchar, Elżbieta Pirianowicz-Chaber, Magdalena Konarowska, Aleksander WIĘCEJ

Design, synthesis and biological evaluation of some novel substituted quinazoline derivatives as antitumor agents

Marwa F. Ahmed, Naja Magdy WIĘCEJ

Design, efficient synthesis, mechanism of reaction and antiproliferative activity against cancer and normal cell lines of a novel class

Huda R.M. Rashdan, Hanaa M.F. Roaiah, Zeinab A.Muhammad, Joanna Wietrzyk, Magdalena Milczarek, Abdelmohsen M. Soliman WIĘCEJ

LC-ESI-Q-TOF-MS determination of phenolic constituents and antioxidant capacity of the extracts from Cistanche salsa

Wirginia Kukula-Koch, Elmira Kartbayeva, Wojciech Koch, Rizvangul Ayupova, Liliya Ibragimova, Kazimierz Głowniak, Ewa Poleszak, Zuriyadda Sakipova WIĘCEJ

Assessment of release of trimetazidine hydrochloride from orally disintegrating tablets (ODTs) using different disintegrants

Beata Sarecka-Hujar, Andrzej Jankowski, Aneta Ostróżka-Cieślik, Radosław Balwierz, Anna Banyś, Renata Dyja, Dariusz Łukowiec, Dominik Marciniak, Janusz Pluta WIĘCEJ

Development and in vitro evaluation of bilayer tablets having an immediate release layer containing donepezil hydrochloride and an extended release layer containing memantine hydrochloride

Timucin Ugurlu, Hatice Canbagi, Tugce Ozaydin WIĘCEJ

In vitro evaluation of aceclofenac monolithic osmotic pump tablets containing a swellable polymer

Timucin Ugurlu, Urun Kandemirer WIĘCEJ

Effect of selected excipients and the preparation method on the parameters of orally disintegrating tablets containing ondansetron

Wioletta Siemiradzka, Beata Szulc-Musioł, Lucyna Bułaś, Andrzej Jankowski WIĘCEJ

Antibiotics residues: stability studies of amoxicillin metabolites – amoxicillin diketopiperazine-2,5-dione and amoxicilloic acid

Magdalena Paulina Ozimek, Dominik Marciniak, Jakub Okoniewski, Witold Ignasiak, Janusz Pluta WIĘCEJ

Proposed strategies for improving the stability of polymeric HPMC matrix tablets: proper selection of excipients and seal coating

Ehab M. Elzayat, Ali A. Abdel-Rahman, Sayed M. Ahmed, Fars K. Alanazi, Walid A. Habib Adel Sakr WIĘCEJ

Application of selected diffractive and microscopic methods to evaluate the physical state of drug and morphology of microspheres obtained by spray

Aneta Ostróżka-Cieślik, Beata Sarecka-Hujar, Tomasz Krzykawski, Jagna Karcz, Anna Banyś, Andrzej Jankowski WIĘCEJ

Formulation and in vitro evaluation of floating tablets of psyllium husk and tragacanth using sitagliptin phosphate as a model drug

Shazia Akram Ghumman, Sahrish Andleeb, Sajid Bashir, Rai Muhammad Sarfraz, Munair Badshah, Majeedullah Sobia Noreen WIĘCEJ

Oleogels and bigels as topical drug carriers for ketoconazole – development and in vitro characterization

Magdalena Wróblewska, Marta Szekalska, Anita Hafner, Katarzyna Winnicka WIĘCEJ

The possible role of high on-aspirin platelet reactivity, hyperhomocysteinemia and inflammation in subacute stent thrombosis

Sławomir Białek, Grażyna Sygitowicz, Jerzy Pręgowski, Jadwiga Janas, Dariusz Sitkiewicz WIĘCEJ

In vitro susceptibility of oral Candida albicans isolates to chlorhexidine

Anna Biernasiuk, Jolanta Szymańska, Agata Kustra, Izabela Korona-Głowniak, Anna Malm WIĘCEJ

Comparative in vitro studies of furazidin and nitrofurantoin activities against common uropathogens including multidrug-resistant strains of E. coli and S. aureus

Karolina Klesiewicz, Elżbieta Karczewska, Paweł Nowak, Paulina Mrowiec, Iwona Skiba-Kurek, Joanna Białecka, Zbigniew Majka, Sylwia Sylwia Berdzik-Kalarus, Alicja Budak, Paweł Zajdel WIĘCEJ

Employment in schizophrenia – students' point of view

Tomasz Zaprutko, Dorota Kopciuch, Dominika Sawicka, Blanka Majchrzycka, Michał Nowak, Michał Michalak, Krzysztof Kus, Elżbieta Nowakowska WIĘCEJ

Opinions of pharmacists on community pharmacy-based health screenings for common chronic diseases

Magdalena Waszyk-Nowaczyk, Oliwier Skura, Michał Michalak, Anna Ratka WIĘCEJ

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Combinations of isothiocyanates with drugs – a chance or threat to chemoprevention and cancer treatment?

Lidia Mielczarek, Zdzisław Chilmończyk, Piotr Suchocki, Piotr Wroczyński, Katarzyna Wiktorska WIĘCEJ

Development and validation of analytical method for assessment of calcium dobesilate in varied hydrogel compositions

Anna Lisik, Ewa Pilch, Laura Słowiak, Witold Musiał WIĘCEJ

Development and validation of RP-HPLC method for simultaneous estimation of tizanidine HCl and meloxicam in bilayer mucoadhesive buccal films

Muhammad Zaman, Muhammad Hanif, Muhammad Wahab Amjad, Hassan Murtaza, Maria Abdul Ghafoor Raja, Kashif Ur Rahman Khan WIĘCEJ

Studies towards hemocompatibility of polyamine conjugates with bicyclic systems

Marta Szumilak, Magdalena Markowicz-Piasecka, Elżbieta Mikiciuk-Olasik, Andrzej Stańczak, Joanna Sikora WIĘCEJ

Chemical transformations of glucose in solutions for peritoneal dialysis after sterilization and during storage

Nataliia Hudz, Karolina Korzeniowska, Piotr P. Wieczorek WIĘCEJ

Development of the UHPLC-DAD method for simultaneous determination of four active pharmacological in-gredients in cannabinoid plant material

Anna Krause, Marek Milewski, Karolina Wielgus, Milena Szalata, Ryszard Słomski, Przemysław Zalewski, Judyta Cielecka-Piontek WIĘCEJ

Synthesis and anticancer activity evaluation of some new derivatives of 2-(4-benzyol-1-piperazinyl)-quinoline and 2-(4-cinnamoyl-1-piperazinyl)-quinoline

Krzysztof P. Kubica, Przemysław P. Taciak, Agnieszka Czajkowska, Alicja Stokfisz-Ignasiak, Rafał Wyrębiak, Piotr Podsadni, Izabela Młynarczuk-Biały, Jacek Malejczyk, Aleksander P. Mazurek WIĘCEJ

Synthesis and anticancer activity evaluation of novel derivatives of 7-amino-4-methylquinolin-2(1h)-one

Krzysztof P. Kubica, Przemyslaw P. Taciak, Agnieszka Czajkowska, Alicja Sztokfisz-Ignasiak, Rafał Wyrębiak, Izabela Młynarczuk-Biały, Jacek Malejczyk, Aleksander P. Mazurek WIĘCEJ

Selective arylation of phenol protected propargyl bromide via Pd-catalysed Suzuki coupling reaction: synthesis, mechanistic studies by DFT calculations and their pharmacological aspects

Hira Farooq, Nasir Rasool, Muhammad Tayyab Ansari, Komal Rizwan, Sarosh Iqbal, Tariq Mahmood, Hira Israr, Khurshid Ayub, Tahir Rasheed, Seema Zareen, Muhammad Nadeem Akhtar WIĘCEJ

1,3-Oxazolidin-5-ones derived from proline as chiral components in the synthesis of predictive enantioselective coupling reagents

Katarzyna Kasperowicz-Frankowska, Beata Kolesińska, Anna Gzik, Konrad Jastrząbek, Zbigniew J. Kamiński WIĘCEJ

Phytoestrogens use by Polish women

Katarzyna Korzeniowska, Artur Cieślewicz, Mariola Pawlaczyk, Michał Pawlaczyk, Anna Jabłecka WIĘCEJ

The phytochemical and antimicrobial examination of phenolic acids contained in extracts from four Marrubium species

Małgorzata Kozyra, Anna Biernasiuk, Remigiusz Antonik, Anna Malm, Grażyna Zgórka WIĘCEJ

Dipsacus fullonum L. leaves and roots – identification of the components of the essential oils and alpha-amylase inhibitory activities of methanolic extracts

Ewa Witkowska-Banaszczak WIĘCEJ

Impact of excipients on pharmaceutical availability of folic acid from tablets

Aneta Ostróżka-Cieślik, Barbara Dolińska, Florian Ryszka WIĘCEJ

Box-Behnken design: a statistical approach to evaluate the effect of crosslinked carboxymethyl cellulose and sodium starch glycolate on release kinetics of drug

Ghulam Abbas, Muhammad Hanif, Akhtar Rasul, Sajid Mahmood Khan, Muhammad Naeem Amir WIĘCEJ

Quercetin ameliorate insulin resistance concomitant early cardiovascular changes in experimental rats

Ajay Singh Kushwah, Ghanshyam Das Gupta WIĘCEJ

Antinociceptive and antianxiety activity of hydroethanolic extracts of three impatiens species in mice

Katarzyna Szewczyk, Jolanta Orzelska-Górka, Magdalena Polakowska, Grażyna Biała WIĘCEJ

A policy view: gaps and weaknesses of substitution between biological products in law and economics dimension: the example of insulin

Katarzyna Anna Gruchała, Piotr Wąż, Piotr Kawczak, Agnieszka Zimmermann, Bogumił Wolnik, Tomasz Bą-czek WIĘCEJ

Molecular fingerprinting of thyroid cancer cells using library of molecular receptors formed by n-lipidated peptides immobilized on cellulose

Justyna Frączyk, Małgorzata Walczak, Waldemar Balcerzak, Katarzyna Pokajewicz, Piotr Wieczorek, Wojciech Młynarski, Wojciech Fendler, Zbigniew J. Kamiński WIĘCEJ

Nurse prescribing. the knowledge of nursing and midwifery students regarding new professional competences. Poland-wide multicenter study

Aleksander Zarzeka, Mariusz Pańczyk, Jarosława Belowska, Lucyna Iwanow, Ilona Cieślak, Nicole Mazur, Berta Paz Lourido, Joanna Gotlib WIĘCEJ

Poles in pharmacy – source of knowledge and prevalence of over the counter usage

Ewa Bandurska, Judyta Zaleska, Marzena Zarzeczna-Baran WIĘCEJ

Legitimacy and potential savings in automatic substitution of biological products in Poland, the example of insulin

Katarzyna Anna Gruchała, Piotr Wąż, Agnieszka Zimmermann WIĘCEJ

Knowledge and attitude of community pharmacy employees towards an automatic drug substitution of generics and biosimilars

Zuzanna Małgorzata Łukasik, Michał Nowicki WIĘCEJ

The effect of multiple-dose paroxetine on the pharmacokinetic profile of carvedilol in rats

Maria B. Abrudan, Dana M. Muntean, Maria A. Neag, Laurian Vlase, Ana-Maria Gheldiu WIĘCEJ

The effect of metronidazole on the viability of cal-27 tongue cancer cells

Natalia Tołoczko-Iwaniuk, Dorota Dziemiańczyk-Pakieła, Katarzyna Celińska-Janowicz, Paweł Drągowski, Dawid Groth, Joanna Reszeć, Halina Car, Jan Borys, Wojciech Miltyk WIĘCEJ

The effect of co-processed dry binder with microcrystalline cellulose on release of verapamil hydrochloride from hydrophilic matrix tablets

Alena Komersová, Václav Lochař, Kateřina Myslíková, Jitka Mužíková, Martin Bartoš WIĘCEJ

The study of adsorption and desorption of antibiotics on the surface of nanoparticles

Paweł Biernat, Beata Borak, Jan Meler, Bożena Karolewicz WIĘCEJ

Formulation and evaluation of indomethacin loaded nanosponges for oral delivery

Nasir Abbas, Komal Sarwar, Amjad Hussain, Muhammad Irfan, Rabia Mehmood, Muhammad Sohail Arshad, Pervaiz Akhtar Shah WIĘCEJ

Release of bioactive substances from formulations containing Arthrospira platensis (Spirulina platensis)

Bożena Muszyńska, Jan Lazur, Agata Krakowska, Barbara Jękot, Agnieszka Szewczyk, Katarzyna Sułkowska-Ziaja, Łukasz Zimmer, Ewa Poleszak, Włodzimierz Opoka WIĘCEJ

Esculetin attenuates neurotoxicity induced by a beta 25-35 in sh-sy5y cells via inhibiting oxidative stress and mito-chondria-mediated apoptosis

Jun-Li Gao, Xiao-Ying Gong WIĘCEJ

UVB protective, anti-aging, and anti-inflammatory properties of aqueous extract of walnut (Juglans regia L.) seeds

Agata Przekora, Anna Belcarz, Katarzyna Kowalczyk, Michał Wójcik, Katarzyna Wojciechowska, Grażyna Ginalska WIĘCEJ

The induction of cytotoxicity by pterostilbene in various human cancer cell lines

Joanna Wawszczyk, Katarzyna Jesse, Aleksandra Szewerniak, Małgorzata Kapral, Ludmiła Węglarz WIĘCEJ

Synthesis and biological evaluation of some new hydrazone derivatives bearing pyrimidine ring as analgesic and anti-inflammatory agents

Kadriye Akdag, Gökhan Ünal, Fatih Tok, Feyza Aricioglu, Halide Edip Temel, Bedia Koçyiđit-Kaymakçioglu WIĘCEJ

New betulin nitrates: synthesis, cytotoxic activity and molecular docking evaluation

Gai-Li Feng, Jin Luo, Min-Jie Xiao, Bao-En He, Yong-Qian Liu, Jun-Xiao Wu, Rong Zhang, Tao Wang WIĘCEJ

The radiolytic studies of doripenem monohydrate in the solid state

Karolina Kilińska, Judyta Cielecka-Piontek, Robert Skibiński, Daria Szymanowska, Andrzej Miklaszewski, Waldemar Bednarski, Przemysław Zalewski WIĘCEJ

Impact of hydrochlorothiazide on the stability of two perindopril salts. Evaluation of the interaction with HPLC and ESI LC/MS methods

Anna Juszczak, Beata Jadwiga Stanisz, Wojciech Szczołko, Martyna Pieszak, Judyta Cielecka-Piontek WIĘCEJ

The content of selenium, polyphenols and antioxidative activity in selected medicinal plants from Poland and western Ukraine

Zofia Sotek, Bożenna Białecka, Bogumiła Pilarczyk, Barna Kruzhel, Radosław Drozd, Renata Pilarczyk, Agnieszka Tomza-Marciniak, Halyna Lysak, Małgorzata Bąkowska, Stakh Vovk WIĘCEJ

Development of a quantitative scoring method for STROBE checklist

Dnyanesh Limaye, Ravi Shankar Pitani, Vaidehi Limaye, Arlan Sydymanov, Christian Otzipka, Patrick Ziesenis, Gerhard Fortwengel WIĘCEJ

Quantitative and qualitative analysis of fixed-dose-combination products (FDC, polypill) applied in polytherapy of hypertensive disease. Review

Mariusz Stolarczyk, Anna Apola, Anna Maślanka, Anna Kwiecień, Włodzimierz Opoka WIĘCEJ

Advances and limitations in pharmacotherapy of epilepsy

Anna Rapacz WIĘCEJ

Cannabinoids as antiemetics: a short review

Hugo Calavia Liano, Przemysław Zakowicz, Przemysław Mikołajczak WIĘCEJ

A therapeutic potential of nicotine: reassessing the current paradigm of nicotine pharmacotherapy, literature review

Marcin Delijewski, Leon Kośmider, Radosław Balwierz, Megan Tomas, Daniel Yi, Bartosz Koszowski, Dominik Marciniak, Bożena Karolewicz WIĘCEJ

Contents

WIĘCEJ

Pełna wersja czasopisma/The entire magazine

WIĘCEJ

Cover 1

WIĘCEJ

Cover 2

WIĘCEJ

Cover 3

WIĘCEJ

Pełna wersja czasopisma/The entire magazine

WIĘCEJ

Cover 1

WIĘCEJ

Cover 2

WIĘCEJ

Cover 3

WIĘCEJ

Contents

WIĘCEJ

Immunotoxins, an advance tool for cancer treatment: review and update

Iqra Munir, Rana Dawood Naseer, Aisha Sultana, Amina Naseer, Bushra Shaukat, Fatima Sultana WIĘCEJ

Stability studies of ceftiofur sodium in aqueous solutions and in the solid phase

Agnieszka Dołhań, Agnieszka Sobczak, Izabela Muszalska, Beata Medenecka, Piotr Garbacki, Szymon Tomczak, Anna Jelińska WIĘCEJ

Screening the specific substrates of adenylation domain from marine actinomycetes by fluorescence quenching and isothermal titration calorimetry

Ming Lei, Zhijuan Zhao, Ke Liu, Yanli Liu, Hui Zhang, Xue Wu, Siying Gong, Yanling Ma, Haobin Zhao, Jinlin Liu, Jinrong Min, Chao Qi WIĘCEJ

Determination of fluoxetine hydrochloride via ion-pair complexation with alizarin red S.

Ioana Clementina Constantinescu, Alexandra Filareta Neagu, Valentina Uivarosi WIĘCEJ

Preparation of scutellarin loaded tpgs polymeric micelles and evaluation of its pharmacokinetics and pharmacodynamics effects in rats

Liu Zou, Shujuan Xiong, Xiangping Deng, Juan Liu, Runde Xiong, Zhe Wang, Xuan Cao, Yanming Chen, Yu Guo, Guo Tao Tang WIĘCEJ

Design, synthesis and analysis of anticancer activity of new SAR-based S16020 derivatives

Beata Tylińska, Ryszard Jasztold-Howorko, Karina Kowalczewska, Katarzyna Szczaurska-Nowak, Tomasz Gębarowski, Joanna Wietrzyk WIĘCEJ

Design, synthesis and anticancer activity evaluation of new quinazoline derivatives linked to thiazolidinone, azetidinone or oxadiazol moieties

Marwa F. Ahmed, Naja Magdy WIĘCEJ

Chemical composition of the essential oil and flavonoids of Thymus serpyllum L., growing on territory of the east Kazakhstan.

Kulyash Tazabayeva, Batiyash Sylibayeva WIĘCEJ

Quercetin influences BSA alpha-helical structures of native, ACR- and NaNO2-modified BSAs

Anna Rorbach-Dolata, Ewa Żurawska-Płaksej, Agnieszka Piwowar WIĘCEJ

Dioscin improves survival in murine endotoxemia induced by lipopolysaccharide

Bing Han, Siyu Tao, Meitong Liu, Zhe Feng, Shuang Guan WIĘCEJ

Evaluation of nutritional and medicinal properties of Bacopa monnieri biomass and preparations

Bożena Muszyńska, Agata Krakowska, Jan Lazur, Agnieszka Szewczyk, Włodzimierz Opoka WIĘCEJ

Cirsium oleraceum L. Scop. inhibits cell viability and decreases secretion of matrix metalloproteinases (MMP2 and MMP9) in glioblastoma cell line

Sylwia K. Naliwajko, Renata Markiewicz-Żukowska, Justyna Moskwa, Irena Kasacka, Krystyna, Gromkowska-Kępka, Patryk Nowakowski, Katarzyna Socha, Maria H. Borawska WIĘCEJ

Physicochemical characteristics of furosemide incorporated eudragit microspheres formulated by spray drying

Aneta Ostróżka-Cieślik, Beata Sarecka-Hujar, Andrzej Jankowski WIĘCEJ

Effects of insulin and embryonic stem cells loaded plga nanoparticles on pancreatic beta TC cells

Çiđdem Yücel, Yeşim Aktaş, Zelihagül Deđim, Şükran Yilmaz, Taibe Arsoy, Levent Altintaş, Can Çokçalişkan, Mahmut Sözmen WIĘCEJ

Protective effect of 6-shogaol against endotoxin-induced periodontitis in rats

Hong Yan Qi, Bing Han WIĘCEJ

Ameliorative effects of dimethyl fumarate in acute and chronic murine models of depression

Loretta O. Iniaghe, Eloho E. Okpakpor, Osaze O. Edosuyi, Ewere O. Eseka, Ogugua I. Nedozi WIĘCEJ

Bridging east with west of europe – a comparison of orphan drugs policies in Poland, Russia and the Netherlands

Marcin Czech, Aleksandra Baran-Kooiker, Malwina Holownia-Voloskova, Coen Kooiker, Jolanta Sykut-Cegielska WIĘCEJ

The civil liability of entities conducting medical activities for damages caused by medicinal products and medi-cal devices under polish law

Agnieszka Rabiega-Przyłęcka WIĘCEJ

Evaluation of pharmaceutical emergency contraceptive services in Poland

Natalia Susłowska, Agnieszka Zimmermann, Aleksandra Gaworska-Krzemińska WIĘCEJ

Factors associated with estimate of high teratogenic risk in females exposed to anti-infective and anti-inflammatory drugs during pregnancy

Iva Grubor, Ljiljana Nikolić, Dejana Ružić Zečević, Dragan Milovanović, Marko Folić, Nikola Rosić, Cesela Radonjić, Slobodan M. Janković WIĘCEJ

Legal and economic identification and assessment ofpharmacy substitution in narrow therapeutic index drugs, on the example of epileptic medications in Poland

Katarzyna Anna Gruchała, Agnieszka Zimmermann, Piotr Wąż, Piotr Kawczak WIĘCEJ